Discovery and Pharmacological Characterization of 1,2, 3,4-Tetrahydroquinoline Derivatives as RORγ Inverse Agonists against Prostate Cancer

0
19
The authors reported the identification, optimization, and evaluation of 1,2,3,4-tetrahydroquinoline derivatives as novel RORγ inverse agonists, starting from high throughput screening using a thermal stability shift assay.
[Acta Pharmacologica Sinica]
AbstractGraphical Abstract