Engineered Nanomicelles Targeting Proliferation and Angiogenesis Inhibit Tumour Progression by Impairing the Synthesis of Ceramide-1-Phosphate

Researchers engineered sub-100 sized nanomicelles targeting proliferation and angiogenesis using an esterase-sensitive phosphocholine-tethered docetaxel conjugate of lithocholic acid (LCA) and a poly(ethylene glycol) derivative of an LCA–combretastatin A4 conjugate.