CD47, a Novel YAP Target Gene, Contributes to Hepatic Stellate Cell Activation and Liver Fibrosis Induced by High-Fat Diet

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The authors employed single-cell RNA sequencing analysis to investigate CD47 expression in HSCs from mice subjected to a high-fat diet. CD47 silencing in HSCs markedly inhibited the expression of fibrotic genes and promoted apoptosis.
[Heliyon]
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