IDH1 Inhibition Potentiates Chemotherapy Efficacy in Pancreatic Cancer

By
Emily Salmini
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0
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Pharmacologic inhibition of wild-type IDH1 with ivosidenib synergized with conventional chemotherapeutics in vitro and potentiated the efficacy of sub-therapeutic doses of these drugs in vivo in murine PDAC models.
[Cancer Research]
Abstract