Transition of Signal Requirement in Hematopoietic Stem Cell Development from Hemogenic Endothelial Cells

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Researchers demonstrated that stem cell factor and thrombopoietin induced engrafting HSCs from embryonic day 11.5 pre-HSC-I in a serum-free and feeder-free culture condition.
[Proceedings of The National Academy of Sciences of The United States of America]
Abstract