Gene Expression Profile of Intestinal Organoids from People with Cystic Fibrosis upon Exposure to Elexacaftor/Tezacaftor/Ivacaftor

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Scientists characterized the effect of elexacaftor/tezacaftor/ivacaftor (ETI) on the transcriptional activity of patient-derived intestinal organoids-derived cells to understand the intracellular processes triggered by ETI and the differences in treatment response.
[Journal of Cystic Fibrosis]
Abstract