Luteolin Detoxifies DEHP and Prevents Liver Injury by Degrading Uroc1 Protein in Mice

By developing a Cy5-modified single-strand DNA-aptamer-based approach targeting di-(2-ethylhexyl) phthalate (DEHP), the authors identified luteolin as a potential drug, which showcasing robust efficacy in detoxifying the DEHP by facilitating the expulsion of DEHP in both mouse primary hepatocytes and livers.