5-Methylcytosine-Modified circRNA-CCNL2 Regulates Vascular Remodeling in Hypoxic Pulmonary Hypertension through Binding to FXR2

Scientists revealed that hypoxia downregulated circCCNL2 expression, and overexpression of circCCNL2 attenuated pulmonary hypertension progression and inhibited the proliferation of pulmonary artery smooth muscle cell.