The Role of LncRNA-MANCR Induced by HIF-1α Drive the Malignant Progression of Pancreatic Cancer by Targeting miRNA-494/SIRT1 Signaling Axis under Hypoxic Conditions

Microarray assays confirmed lncRNA-MANCR expression in the tissues of patients with pancreatic cancer and patients with chronic pancreatitis, which positively correlated with sirtuin-1 mRNA levels.