Intranasal Vaccination with Multi-Neuraminidase and M2e Virus-Like Particle Vaccine Results in Greater Mucosal Immunity and Protection against Influenza Than Intramuscular Injection

Scientists reported that multi-subtype neuraminidase and M2 ectodomain repeatvirus-like particle vaccine conferred higher efficacy of broad cross-protection after two doses of intranasal delivery than intramuscular injection.