A Genome-Wide Association Study Integrated With Single-Cell and Bulk Profiles Uncovers Susceptibility Genes for Nasopharyngeal Carcinoma Involved in Tumorigenesis Via Regulation of T Cells

Scientists performed in-depth bioinformatic analysis and functional experiments for EOMES, finding that the nasopharyngeal carcinoma-risk alleles of four functional SNPs upregulate EOMES expression by promoting the activity of regulatory elements in T cells.