Neutrophils and Neutrophil Extracellular Traps: Double-Edged Swords in Cancer Pathophysiology and Therapy Resistance

Neutrophils have garnered focus in cancer research due to their participation in cancer initiation, proliferation and metastasis. As important players in the tumor microenvironment, tumor-associated neutrophils are viewed as “a double-edged sword” in cancer pathophysiology.