FUT3 Mediated GRP78 Fucosylation Promotes Colorectal Cancer Survival and Proliferation under Glucose Restriction via PERK/ATF4/STC2 Axis

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The authors demonstrated that colorectal cancer cells exhibit high expression of FUT3 under glucose-deficient conditions and that FUT3 directly binds to GRP78, inducing its fucosylation.
[NPJ Precision Oncology]
Abstract