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Investigators identified poly(ADP-ribose) polymerase 1 (PARP1) as a critical driver of endothelial-to-mesenchymal transition in ischemic heart failure.
[Acta Pharmacologica Sinica]
Endothelial PARP1 Orchestrates Endothelial-to-Mesenchymal Transition via the PARylation of FHL2 in Ischemic Heart Failure
