NewslettersProstate Cell News Lactate-Induced H3K4me3 Histone Mark Promotes PLOD1-Driven Prostate Cancer Invasion By Emily Salmini - July 10, 2026 0 1 Investigators showed that the lactic acid-induced increase in succinate levels affects the activating H3K4me3 methylation mark in prostate cancer cells, promoting a pro-invasive phenotype. [Cell Death & Disease] Abstract