Cilia Beating of Ependymal Cells Regulates Adult Neural Stem Cell Quiescence via Mechanical Forces Mediated by PKD1/2-TRPM3

The authors developed an approach to transiently inhibit the cilia beating of ependymal cells (ECs) lining the forebrain ventricle, showing that EC cilia beating regulates neural stem cell (NSC) quiescence and activation dynamics.