Optimization of a PDMS-Based Cell Culture Substrate for High-Density Human-Induced Pluripotent Stem Cell Adhesion and Long-Term Differentiation into Cardiomyocytes under a Xeno-Free Condition

The authors found that the PDMS substrate coated with a combination of polydopamine and laminin-511 E8 fragments coud support hiPSC attachment and growth for the long term and satisfy their demands of differentiation into cardiomyocytes