Exosomal miR-146a-5p and miR-155-5p Promote CXCL12/CXCR7-Induced Metastasis of Colorectal Cancer by Crosstalk with Cancer-Associated Fibroblasts

Investigators found a significant positive correlation between C-X-C motif chemokine receptor 7 (CXCR7) expression and cancer-associated fibroblast activation markers in colonic tissues from clinical specimens and in villin–CXCR7 transgenic mice.