Apoptotic Extracellular Vesicles Alleviate PG-LPS Induced Inflammation of Macrophages via AMPK/SIRT1/NF-κB Pathway and Inhibit Adjacent Osteoclasts Formation

Researchers extracted apoptotic extracellular vesicles (ApoEVs) from bone marrow MSCs and found ApoEVs inhibited macrophages polarizing into the pro-inflammatory condition via AMPK/SIRT1/NF-κB pathway.