Isoorientin Attenuates Doxorubicin-Induced Cardiac Injury via the Activation of MAPK, Akt, and Caspase-Dependent Signaling Pathways

The authors investigated the effect and mechanism of the natural flavonoid isoorientin combined with doxorubicin (DOX) on the proliferation of tumor cells and improve the survival rate of DOX-injured cardiomyocytes.