Mogrol Suppresses Lung Cancer Cell Growth by Activating AMPK-Dependent Autophagic Death and Inducing p53-Dependent Cell Cycle Arrest and Apoptosis

Mogrol significantly inhibited the proliferation and migration of lung cancer cells, including non-small-cell lung carcinoma cells, A549, H1299, H1975 and SK-MES-1 cells, with no obvious effect on control human bronchial epithelial cells.