Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
Organoid News
Organoid News is an online resource dedicated to the latest research about and featuring organoids.
Subscribe|Follow Us On
Bayesian Modeling of Gene Regulatory Networks in Colorectal Cancer Organoids
[IEEE Transactions on Cybernetics] Investigators propose, for the first time, a comprehensive Bayesian framework to model gene expression dynamics throughout the developmental trajectory of colorectal tumoroids.
Wide-Field Optical Redox Imaging with Leading-Edge Detection Enables Assessment of Treatment Response and Heterogeneity in Patient-Derived Cancer Organoids
[Cancer Research] Researchers assessed and predicted patient-derived cancer organoid response to treatments based on mutational profiles using label-free wide-field optical redox imaging.
Engineering an Organoid Culture System for Enhanced Murine and Human Hematopoietic Stem and Progenitor Cell Self-Renewal and Expansion
[Biofabrication] Scientists suggested that the GelMA-P-T-based biomimetic culture system has the potential to advance the clinical application of expanded hematopoietic stem and progenitor cells and accelerate the development of bone marrow organoid technology.
Mechanistic Insights Into Recurrent Implantation Failure: The Lactate-H3K18la-SLC7A11 Axis Explored via Endometrial Organoid and Blastoid-Endometrial Cell Implantation Models
[Cell Proliferation] Utilizing human endometrial organoids, researchers demonstrated that lactate enhances human endometrial receptivity by promoting epithelial–mesenchymal transition and upregulating histone H3 lysine 18 lactylation.
Production of Clinical Grade Patient iPSC-Derived 3D Retinal Organoids Containing Transplantable Photoreceptor Cells
[Stem Cell Research & Therapy] Retinal organoids were generated using a stepwise 3D differentiation protocol testing different current good manufacturing practice (cGMP) compliant reagents and oxygen tension in a cGMP compliant Biospherix cell culture isolator.
Synergistic Promotion of Bone Regeneration through Co-Culture of Endothelial Cells with Mesenchymal Stem Cells in Endochondral Ossification Organoids
[Stem Cell Research & Therapy] Co-culturing endothelial cells with mesenchymal stem cells in endochondral ossification organoids enhances bone regeneration, offering a promising alternative to traditional tissue engineering strategies.
A Microfluidic Platform for Culturing and High-Content Imaging of Adult Stem Cell-Derived Organoids
[Scientific Reports] Investigators presented the OrganoidChip+, an all-in-one microfluidic device designed to integrate both culturing and high-content imaging of adult stem cell-derived organoids all within one platform.
Interaction Between Gastric Cancer Organoids and Peritoneal Mesothelial Cells Suppresses the Growth of Gastric Cancer Organoids and Induces Drug Resistance
[Human Cell] Scientists investigated the mechanism of drug resistance in peritoneal metastasis, cancer organoids were established from the ascites of a patient with peritoneal metastases of gastric cancer.
Application of Nanomaterials in Organoid Culture and Cryopreservation
[Nanoscale Advances] The authors comprehensively discuss the recent advancements in nanomaterial-based strategies for organoid fabrication and cryopreservation while addressing their challenges such as biocompatibility, scalability, and long-term safety.
ChristianaCare Launches Organoid Core to Personalize Cancer Treatment
[ChristianaCare] ChristianaCare’s Cawley Center for Translational Cancer Research has unveiled a first-of-its-kind organoid core in a community cancer center program. The new laboratory facility within the Helen F. Graham Cancer Center & Research Institute grows and tests living, patient-derived tumor models, giving doctors and researchers a faster, more precise way to identify the therapies most likely to work for each patient.
Cortical Organoid-Derived Models of the Melanoma Brain Metastatic Niche Enable Prioritization of Cancer-Targeting Drugs
[Cell Reports Methods] To understand and target vulnerabilities of human metastases in a brain niche context, investigators developed reproducible melanoma brain metastasis models for metastasis-integrating drug screening.
Ex Vivo Lung-Organoid Model for Aberrant Basaloid Cell Induction and Activation
[Inflammation and Regeneration] Researchers developed an ex vivo murine lung-organoid model designed to induce and activate aberrant basaloid cells. The organoids were subjected to bleomycin stimulation.
Organoids are three-dimensional cell cultures that more accurately model cell behavior, organ function, and pathology than traditional two-dimensional cell culture. Organoid News was launched in 2020 to help scientists stay up-to-date with this revolutionary new research system. Use Organoid News to stay current with the latest applications and discoveries using organoids, as well as new reviews, jobs, news, and upcoming events.
