CD133

[Heliyon] Researchers investigated melatonin's antitumor molecular mechanisms to inhibit the proliferation of HepG2 cells.

[Molecular and Cellular Biochemistry] C57BL/6 mice were used to isolate and identify CD133+GFAP+CD117+Sca1+ cells in the hippocampal dentate gyrus region of the mouse brain as a novel neural stem cell population, in terms of cell phenotype, self-renewal capacity, and differentiation capability.

[Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences] Scientists summarize the current knowledge of the role of CD133 expression in gastic cancer and aim to contribute at identifying promising new strategies for treatment and management of gastric cancer.

[Molecular Biology Reports] Researchers demonstrated that As2O3 had a remarkable inhibitory effect on tumor initiating cells of small cell lung cancer both in vitro and in vivo, and the mechanism might have involved the down-regulation of Notch pathway

[Laboratory Investigation] Brain tissues were clinically collected from 50 patients with glioblastoma and 35 patients with acute craniocerebral injury, followed by immunohistochemical detection of the expression patterns of Forkhead box M1, anterior gradient 2, and hypoxia-inducible factor-1α.

[International Journal of Oncology] The expression and effect of miR‑1291 in colorectal cancer cells (CRC) was investigated. It was identified that miR‑1291 significantly suppressed the proliferation, invasion, cell mobility and colony formation of CRC cells.