Tag results:
CD8
Pancreatic Cell News
CCL2-Mediated Monocytes Regulate Immune Checkpoint Blockade Resistance in Pancreatic Cancer
[International Immunopharmacology] Scientists found that C-C motif chemokine ligand 2 (CCL2) recruits monocytes to and decrease CD8+ T cell infiltration in pancreatic tumors.
Immune Regulation News
The Development of Chiral Nanoparticles to Target NK Cells and CD8+ T Cells for Cancer Immunotherapy
[Advanced Materials] Researchers investigated the immunological effect of chiral nanomaterials as therapeutic and preventive options against tumors.
Immunology of Infectious Disease News
Viral PB1-F2 and Host IFN-γ Guide ILC2 and T Cell Activity during Influenza Virus Infection
[Proceedings of the National Academy of Sciences of the United States of America] In the absence of IFN-γ, lung innate lymphoid cells (ILC12) from mice challenged with the A/California/04/2009 H1N1 virus, containing nonfunctional viral PB1-F2, initiated a robust IL-5 response, which also led to improved tissue integrity and increased survival.
Immune Regulation News
Themis Is Indispensable for IL-2 and IL-15 Signaling in T Cells
[Science Signaling] The authors investigated whether Themis plays a direct role in cytokine signaling in mature T cells.
Immunology of Infectious Disease News
Spatial, Temporal and Molecular Dynamics of Swine Influenza Virus-Specific CD8 Tissue Resident Memory T Cells
[Mucosal Immunology] Most nucleoprotein-specific CD8 T cells in broncho-alveolar lavage and lung are tissue resident memory cells that express CD69 and downregulate CD45RA and CCR7.
Cell Therapy News
Defined Tumor Antigen-Specific T Cells Potentiate Personalized TCR-T Cell Therapy and Prediction of Immunotherapy Response
[Cell Research] T cells engineered with T cell receptors (TCRs) from naturally occurring tumor antigen-specific T cells in a patient will target personal tumor-specific antigens in their tumor.