Tag results:
EMT
Cancer Stem Cell News
The Ubiquitin E3 Ligase ARIH1 Regulates hnRNP E1 Protein Stability, EMT and Breast Cancer Progression
[Oncogene] Investigators demonstrated that hnRNP-E1 protein stability was increased upon ARIH1 silencing, whereas, overexpression of ARIH1 leads to a reduction in hnRNP-E1.
Cancer Stem Cell News
Breast Cancer Circulating Tumor Cells with Mesenchymal Features—an Unreachable Target?
[Cellular and Molecular Life Sciences] Scientists provide a comprehensive review of clinical significance of mesenchymal circulating tumor cells in breast cancer together with statistical analysis of previously published data.
Mammary Cell News
Hypoxia-Induced lncRNA RBM5-AS1 Promotes Tumorigenesis via Activating Wnt/β-Catenin Signaling in Breast Cancer
[Cell Death & Disease] Overexpression of RBM5-AS1 facilitated proliferation, migration, invasion, EMT, and stemness maintenance of breast cancer cells in vitro and in vivo.
Mammary Cell News
Ultrasound Targeted Microbubble Destruction-Mediated SOCS3 Attenuates Biological Characteristics and Epithelial-Mesenchymal Transition (EMT) of Breast Cancer Stem Cells
[Bioengineered] The authors explored the effects of ultrasound targeted microbubble destruction -mediated transfection of SOCS3 on the biological characteristics and EMT of breast cancer stem cells.
ESC & iPSC News
CDH18 Is a Fetal Epicardial Biomarker Regulating Differentiation towards Vascular Smooth Muscle Cells
[NPJ Regenerative Medicine] Scientists recapitulated epicardiogenesis using human iiPSCs and identified type II classical cadherin CDH18 as a biomarker defining lineage specification in human active epicardium.
Pulmonary Cell News
A Comparative Study on the Model of PM2.5 Direct or Indirect Interaction with Bronchial Epithelial Cells
[Environmental Science and Pollution Research] The authors examined the viability of BEAS-2B and mRNA/protein expression profile of oxidative stress and inflammatory response-related transcription factors Nrf2, NF-kB, and according inflammatory indicators such as IL-1, IL-6, and IL-8, with a view to evaluating the effects of different interaction models of PM2.5 on epithelial cell damage in vitro.