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Gata4
ESC & iPSC News
GATA6 Mutations in hiPSCs Inform Mechanisms for Maldevelopment of the Heart, Pancreas, and Diaphragm
[eLife] To define molecular mechanisms for the damaging cardiac outflow tract defects caused by GATA6 variants, scientists studied transcriptional and epigenetic responses to GATA6 loss of function and missense variants during cardiomyocyte differentiation of isogenic human iPSCs.
ESC & iPSC News
12-O-Tetradecanoylphorbol-13-Acetate Increases Cardiomyogenesis through PKC/ERK Signaling
[Scientific Reports] Scientists showed that 12-O-tetradecanoylphorbol-13-acetate can be applied as a cardiomyogenesis-promoting factor for the differentiation of mouse embryonic stem cells in vitro.