HIV

[Journal of Medical Virology] The authors examined distribution of the well-characterized +874 T/A IFN-γ and -509C/T TGF-β1 single nucleotide polymorphisms in Thai people living with HIV.

[Immunity & Ageing] Researchers established a semi-mechanistic population model simultaneously describing naïve and memory CD4+ T cell trajectories in 122 participants.

[Ebiomedicine] Lymphocytes and tissue sections of lymph node were collected from 11 HIV-1 positive antiretroviral therapy (ART)-naive and 19 HIV-1 negative donors.

[Stem Cell Reviews and Reports] Mesenchymal stem cells appear to have the potential to contribute to the HIV-1 reservoir. Further studies are needed using techniques such as those used to prove that cluster of differentiation (CD)4+ T cells constitute an HIV-1 reservoir before a reservoir function can definitively be ascribed to MSCs.

[Journal of Molecular Biology] Scientists identified a transcriptional signature associated with progressive resistance to HIV infection in CD4+ T cells.

[Microbial Pathogenesis] A brief account of the polymorphism in the APOBEC3G, TRIM5α, and BST2 genes are explored among different populations along with the interaction of APOBEC3G with Vif protein.