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HUVECs
Mesenchymal Cell News
Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Loaded with miR-223 Ameliorate Myocardial Infarction through P53/S100A9 Axis
[Genomics] The authors explored the mechanism of human umbilical cord MSCs-derived extracellular vesicles loaded with miR-223 on myocardial infarction.
Endothelial Cell News
MiR-29b-3p Inhibits the Inflammation Injury in Human Umbilical Vein Endothelial Cells by Regulating SEC23A
[Biochemical Genetics] The authors investigated the effects of miR-29b-3p on the inflammation injury of HUVECs induced by lipopolysaccharide and explored the underlying mechanisms.
Endothelial Cell News
Scutellarin Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting TNFα-Induced Vascular Endothelial Barrier Breakdown
[Acta Pharmacologica Sinica] Researchers suggested that Scutellarin reduced triple-negative breast cance metastasis by suppressing tumor necrosis factor-α (TNFα)-initiated vascular endothelial barrier breakdown through rescuing the reduced expression of junctional proteins by regulating the TNF receptor 2-extracellular signal-regulated protein kinase1/2-enhancer of zeste homolog-2 signaling pathway.
Endothelial Cell News
Trimetazidine Enhances Myocardial Angiogenesis in Pressure Overload-Induced Cardiac Hypertrophy Mice through Directly Activating Akt and Promoting the Binding of HSF1 to VEGF-A Promoter
[Acta Pharmacologica Sinica] The authors investigated the effects of TMZ on myocardial angiogenesis in pressure overload-induced cardiac hypertrophy mice.
Endothelial Cell News
Raised SPINK1 Levels Play a Role in Angiogenesis and the Transendothelial Migration of ALL Cells
[Scientific Reports] In a co-culture system of human umbilical vein endothelial cells and acute lymphoblastic leukemia (ALL) cells, serine protease inhibitor Kazal type 1 (SPINK1) exposure resulted in enhanced endothelial cell motility and ALL cells trans-endothelial migration.
Mesenchymal Cell News
Human Adipose Mesenchymal Stem Cells Modulate Inflammation and Angiogenesis through Exosomes
[Scientific Reports] Researchers investigated the anti-inflammatory and pro-angiogenic roles of human adipose MSC-derived exosomes, focusing on the underlying mechanisms.