Scutellarin Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting TNFα-Induced Vascular Endothelial Barrier Breakdown

Researchers suggested that Scutellarin reduced triple-negative breast cance metastasis by suppressing tumor necrosis factor-α (TNFα)-initiated vascular endothelial barrier breakdown through rescuing the reduced expression of junctional proteins by regulating the TNF receptor 2-extracellular signal-regulated protein kinase1/2-enhancer of zeste homolog-2 signaling pathway.