Nanog

[Cell Death & Disease] Scientists identified a novel lncRNA 408 (lnc408) in epithelial–mesenchymal transition-related breast CSCs (BCSCs). The lnc408 is high expressed in BCSCs in vitro and in vivo.

[Cancer Cell International] Colorectal cancer spheroids were developed using hanging drop and forced floating in serum-free and non-attachment conditions and their morphological features were evaluated by scanning electron microscopy.

[Stem Cells] Researchers investigated how murine ESCs sense fluid shear stress and modulate a non‐canonical Wnt signaling response to promote pluripotency.

[Cell Death & Disease] Scientists proposed a novel mechanism for transcription factor EB (TFEB) governing pluripotency of mESCs by regulating the pluripotency transcriptional network.

[Epigenomics] The authors reviewed the molecular basis of reprogramming, including the reprogramming factors, applied vectors and epigenetic modifications to provide a comprehensive guide for reprogramming studies.

[Life Sciences] The authors demonstrated that the miRNA miR-142-3p directly targeted the 3′ untranslated region of HMGA2, which encoded an onco-embryonic protein that was overexpressed in most cancers, including breast cancer.