Human Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Alleviate Lung Injury in Rat Model of Bronchopulmonary Dysplasia by Affecting Cell Survival and Angiogenesis

Researchers found that human umbilical cord MSCs-derived small extracellular vesicles were successfully absorbed by lung tissue after intratracheal administration, and remained in the lungs for at least 72 hours.
[Stem Cells and Development]
You, J., Zhou, O., Liu, J., Zou, W., Zhang, L., Tian, D., Dai, J., Luo, Z., Liu, E., Fu, Z., & Zou, L. (2020). Human Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Alleviate Lung Injury in Rat Model of Bronchopulmonary Dysplasia by Affecting Cell Survival and Angiogenesis. Stem Cells and Development. https://doi.org/10.1089/scd.2020.0156 Cite
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LncRNA BCYRN1 Inhibits Glioma Tumorigenesis by Competitively Binding with miR-619-5p to Regulate CUEDC2 Expression and the PTEN/AKT/p21 Pathway

Three fresh tumor tissues from glioma patients and three normal brain tissues from craniocerebral trauma patients were prepared for high-throughput RNA sequencing.
[Oncogene]
Mu, M., Niu, W., Zhang, X., Hu, S., & Niu, C. (2020). LncRNA BCYRN1 inhibits glioma tumorigenesis by competitively binding with miR-619-5p to regulate CUEDC2 expression and the PTEN/AKT/p21 pathway. Oncogene, 1–14. https://doi.org/10.1038/s41388-020-01466-x Cite
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E2F7−EZH2 Axis Regulates PTEN/AKT/mTOR Signaling and Glioblastoma Progression

Functional studies showed that E2F7 promoted cell proliferation, cell-cycle progression, cell metastasis and tumorigenicity abilities in vitro and in vivo.
[British Journal of Cancer]
Yang, R., Wang, M., Zhang, G., Bao, Y., Wu, Y., Li, X., Yang, W., & Cui, H. (2020). E2F7−EZH2 axis regulates PTEN/AKT/mTOR signalling and glioblastoma progression. British Journal of Cancer, 1–11. https://doi.org/10.1038/s41416-020-01032-y Cite
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