RAGE

[Journal of Experimental & Clinical Cancer Research] The authors demonstrated that enhanced secretory autophagy in glioblastoma (GB) facilitated M1-like polarization of tumor associated macrophages to enhance temozolomide sensitivity of GB cells.

[American Journal of Respiratory and Critical Care Medicine] Alveolar and endothelial injury may be differentially associated with COVID-19 disease severity over time. The authors described alveolar and endothelial injury dynamics and associations with COVID-19 severity, cardiorenovascular injury, and outcomes.

[American Journal of Respiratory and Critical Care Medicine] Scientists describe alveolar and endothelial injury dynamics and associations with COVID-19 severity, cardiorenovascular injury, and outcomes.

[Molecules] Scientists investigated whether the autophagy inhibitor chloroquine could potentiate the anticancer effect of pterostilbene in the PDAC cell lines MIA PaCa-2 and BxPC-3, as well as in an orthotopic animal model.

[Experimental Cell Research] Researchers examined the involvement of advanced glycation end (AGE)-related receptors on AGE-induced angiogenesis in endothelial cells.

[Scientific Reports] Scientists analyzed the effect of obesity on advanced glycation endproducts (AGEs) accumulation, AGE-receptors and AGE-detoxification, and whether the absence of RAGE may have improved hepatosteatosis and inflammation, by comparing the liver of lean control, obese and obese RAGE-deficient mice.