T cells

[Nature Communications] Researchers characterized the function of tumor-derived PGRN in promoting immune evasion in primary pancreatic ductal adenocarcinoma.

[Science] Scientists developed a therapeutic approach to generate transient antifibrotic CAR T cells in vivo by delivering modified mRNA in T cell–targeted lipid nanoparticles.

[Frontiers in Immunology] Scientists examined the effect of selectively blocking the function of sCTLA-4 on in vitro immune responses from volunteer healthy or melanoma patient PBMC samples.

[Genome Medicine] Scientists adapted a B cell pipeline for undocumented alleles, genotype, and haplotype inference for full and partial adaptive immune receptor repertoire sequencing T cell receptor data sets.

[Journal of Ovarian Research] Treatment with R10 fraction, isolated from garlic, was performed and the alterations in hormonal levels, T cell polarization markers, and expression of fertility-related genes were evaluated.

[Cellular & Molecular Immunology] Scientists highlight how the use of high-resolution mass spectrometry to analyze T cell proteomes can improve our understanding of how these processes are regulated.