TGFBR1

[Cell Communication and Signaling] Researchers studied the functions of umbilical cord MSCs-released extracellular vesicles and their implicated molecules in mesangial proliferative glomerulonephritis.

[Ecotoxicology and Environmental Safety] Researchers explored whether human umbilical cord MSC-Exos affected the activation of fibroblasts to alleviate pulmonary fibrosis.

[Cellular and Molecular Life Sciences] The in vitro model used human aortic vascular smooth muscle cells to assess the implications of TLR4 transactivation of the TGFBR1 in vascular pathophysiology.

[Experimental Cell Research] Flow cytometry and sphere formation assays indicated that LINC01232 significantly promoted non-small cell lung carcinoma cell stemness.

[Communications Biology] Researchers demonstrated that SMAD specific E3 ubiquitin protein ligase 2 (SMURF2)Thr249 phosphorylation played an essential role in maintaining glioma stem cell (GSC) stemness and tumorigenicity. SMURF2 silencing augmented the self-renewal potential and tumorigenicity of patient-derived GSCs.

[Journal of Biological Chemistry] Investigtors established a system-wide profile of the KRAS-regulated kinase signaling network in KRAS-mutant pancreatic ductal adenocarcinoma.