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adipocytes

Wnt/ß-Catenin-Mediated p53 Suppression Is Indispensable for Osteogenesis of Mesenchymal Progenitor Cells

[Cell Death & Disease] Using conditional lineage-tracing mice, scientists demonstrated that chondrocytes gave rise to a sizable fraction of mesenchymal progenitor cells, which served as progenitors of chondrocyte-derived osteoblasts.

Endocrine Role of Bone in the Regulation of Energy Metabolism

[Bone Research] The authors summarize the regulatory effect of bone and bone-derived factors on energy metabolism and discuss directions for future research.

Alternative Regulatory Mechanism for the Maintenance of Bone Homeostasis via STAT5-Mediated Regulation of the Differentiation of BMSCs Into Adipocytes

[Experimental & Molecular Medicine] Researchers generated adipocyte-specific Stat5 conditional knockout mice to investigate the role of STAT5 in the adipogenesis of bone marrow mesenchymal stem cells (BMSCs).

The Effects of Locomotion on Bone Marrow Mesenchymal Stem Cell Fate: Insight Into Mechanical Regulation and Bone Formation

[Cell and Bioscience] Scientists summarize the regulatory effects of locomotion/mechanical loading on bone marrow MSCs activities.

Adipocyte-Like Signature in Ovarian Cancer Minimal Residual Disease Identifies Metabolic Vulnerabilities of Tumor Initiating Cells

[JCI Insight] Investigators performed dense multi-region transcriptomics analysis of paired biopsies from 17 ovarian cancer patients before and after chemotherapy.

Endothelial Angiogenic Activity and Adipose Angiogenesis Is Controlled by Extracellular Matrix Protein TGFBI

[Scientific Reports] Researchers demonstrated that transforming growth factor-beta induced suppressed angiogenesis stimulated by adipocyte-conditioned medium, both in vitro and in vivo.

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