alveolar epithelial cells

[Scientific Reports] we aim to characterize microvesicles shed from pneumolysin-stimulated alveolar epithelial cells and explore their contribution in mediating crosstalk with neutrophils.

[Proceedings of the National Academy of Sciences of the United States of America]

[Stem Cells and Development] Researchers induced human umbilical cord (hUC)-MSCs to differentiate into type 2 alveolar epithelial cells (AEC2s), and provided evidence that intratracheal transplantation of hUC-MSC-derived AEC2s could improve mortality and alleviate fibrosis in bleomycin-induced pulmonary fibrosis mice.

[EMBO Reports] Using a vascularised lung‐on‐chip model, scientists found that infection of alveolar epithelial cells leads to limited apical release of virions, consistent with reports of monoculture infection.

[Scientific Reports] Investigators utilized a neonatal rat model of bronchopulmonary dysplasia to assess if hyperoxia stimulates lung release of circulating extracellular vesicles(EVs) and if these EVs induce lung and brain injury.

[Stem Cell Research & Therapy] The therapeutic effects of umbilical cord MSC-derived extracellular vesicleson pulmonay fibrosis were evaluated using bleomycin-induced mouse models.