Allogeneic Hematopoietic Cell Transplantation for Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Investigators reported on all 17 patients with BPDCN who underwent allogeneic hematopoietic cell transplantation (allo-HCT) at their center between 2000 and 2020, and concluded that allo-HCT provided long-lasting remissions in BPDCN patients, particularly when performed in complete remission.
[Bone Marrow Transplantation]
[zotpress userid=’7992332′ items=’AAAAAAAA’ style=’apa’ cite=’yes’]
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Plasmacytoid Dendritic Cell Expansion Defines a Distinct Subset of RUNX1-Mutated Acute Myeloid Leukemia

Investigators characterized patients with AML with plasmacytoid dendritic cells (pDC) expansion, which they observed in ∼5% of AML cases. pDC-AMLs often possessed cross-lineage antigen expression and have adverse risk stratification with poor outcome.
[Blood]
[zotpress userid=’6445212′ items=’7Z8NSH3Y’ style=’apa’ cite=’yes’]
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