breast cancer cells

[Laboratory Investigation] Investigators provided evidence that elevated levels of human SMO showed a strong correlation with elevated levels of insulin-like growth factor 1 receptor and reduced survival in diffuse large B-cell lymphoma.

[Scientific Reports] The authors found that a small molecule phenylbutenoid dimer NMac1, a previously identified anti-metastatic agent, had novel anti-proliferative effect only under glucose starvation in metastatic breast cancer cells.

[Military Medical Research] Researchers evaluated the antitumor activities of LR004-VC-MMAE against epidermal growth factor receptor (EGFR)-positive TNBC and further studied its possible mechanism of antitumor action.

[Dalton Transactions] For the development of anticancer drugs with higher activity and reduced toxicity, two approaches were combined: preparation of platinum complexes exhibiting higher stability compared to their platinum counterparts and loading them into mesoporous silica SBA-15.

[Scientific Reports] Researchers developed a protocol for processing human adipose derived MSC secretome formulation of varying concentration. Its molecular composition was evaluated, and its effectiveness in vitro using breast cancer cell lines.

[Cell Death & Disease] Investigators demonstrated that MLK4 promoted TNBC chemoresistance by regulating the pro-survival response to DNA-damaging therapies and identified a novel function of MLK4 in the regulation of DNA damage response signaling.