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breast cancer cells

The Long Non-Coding RNA ET-20 Mediates EMT by Impairing Desmosomes in Breast Cancer Cells

[Journal of Cell Science] Researchers reported the identification of 114 novel long non-coding RNAs that changed their expression during TGFβ-induced epithelial-mesenchymal transition in murine breast cancer cells.

MINDY1 Promotes Breast Cancer Cell Proliferation by Stabilizing Estrogen Receptor α

[Cell Death & Disease] The authors identified MINDY1, a member belongs to the motif interacting with Ubcontaining novel DUB family (MINDY), as a potential deubiquitylase of estrogen receptor α in breast cancer.

Sauchinone Inhibits the Proliferation, Migration and Invasion of Breast Cancer Cells by Suppressing Akt-CREB-MMP13 Signaling Pathway

[Bioscience Reports] Scientists investigated the effects of sauchinone on the growth of breast cancer cells along with the underlying molecular mechanisms. Their results showed that sauchinone treatment markedly inhibited the proliferation, migration, and invasion of breast cancer cells.

Targeting Neurons in the Tumor Microenvironment with Bupivacaine Nanoparticles Reduces Breast Cancer Progression and Metastases

[Science Advances] The authors designed PEGylated lipid nanoparticles loaded with a non-opioid analgesic, bupivacaine, to target neurons within breast cancer tumors and suppress nerve-to-cancer cross-talk.

RNA Binding Protein RBMS3 Is a Common EMT Effector That Modulates Triple-Negative Breast Cancer Progression via Stabilizing PRRX1 mRNA

[Oncogene] Scientists identified RNA Binding Motif Single Stranded Interacting Protein 3 (RBMS3) as a novel and common effector of epithelial-to-mesenchymal transition (EMT), which could be a promising therapeutic target for triple-negative breast cancer treatment.

Transmembrane Protein 97 Exhibits Oncogenic Properties via Enhancing LRP6-Mediated Wnt Signaling in Breast Cancer

[Cell Death & Disease] Researchers revealed that transmembrane protein 97 was a positive modulator of canonical Wnt signaling which was implicated in the tumorigenesis of breast cancer.

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