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breast cancer

Herceptin-Conjugated Magnetic Polystyrene-Agsbox Nanoparticles as a Theranostic Agent for Breast Cancer

[Journal of Biomaterials Applications] Researchers demonstrated selective binding, effective uptake of herceptin (HER)-conjugated magnetic polystyrene-Agsbox nanoparticles into MDA-MB-231and SKBR-3 cell lines with no effect against L929.

A Review of Prognostic and Predictive Biomarkers in Breast Cancer

[Clinical and Experimental Medicine] By combining established prognostic factors with valid prognostic/predicted biomarkers, scientists can start the journey to personalized treatment for every recently diagnosed breast cancer patient.

Updates on Breast Biomarkers

[Virchows Archiv] The authors cover the evolution and latest updates of the CAP/ASCO guidelines relevant to these two important biomarkers in breast cancer.

Autophagy Inhibits Cancer Stemness in Triple-Negative Breast Cancer via miR-181a-Mediated Regulation of ATG5 and/or ATG2B

[Molecular Oncology] The authors identified that autophagy flux was inhibited in triple-negative breast cancer (TNBC) stem cells. miRNA-181a (miR-181a) expression is upregulated both in TNBC CSCs and patient tissues.

Low Glucose-Induced Overexpression of HOXC-AS3 Promotes Metabolic Reprogramming of Breast Cancer

[Cancer Research] Researchers revealed a critical role for HOXC-AS3 in regulating the metabolic reprogramming of breast cancer cells under metabolic stress.

STAT3 Induces Breast Cancer Growth via ANGPTL4, MMP13 and STC1 Secretion by Cancer Associated Fibroblasts

[Oncogene] Researchers demonstrated that STAT3 was essential for the pro-tumorigenic functions of murine breast cancer cancer associated fibroblasts both in vitro and in vivo, and identified a STAT3 signature significantly enriched for genes encoding for secreted proteins.

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