Tag results:
cancer stem cells
Cancer Stem Cell News
Targeting the Metabolism of Cancer Stem Cells by Energy Disruptor Molecules
[Critical Reviews in Oncology/Hematology] Investigators highlight the differences between regular cancer cells and CSC metabolism and discuss the action mechanisms of energy disruptors at the cellular and molecular levels.
Cancer Stem Cell News
Advances in Glioma-Associated Oncogene (GLI) Inhibitors for Cancer Therapy
[Investigational New Drugs] The authors review direct and indirect inhibitors of glioma-associated oncogene homolog (GLI); summarize the abundant active structurally diverse natural GLI inhibitors.
Cancer Stem Cell News
Elevated ATGL in Colon Cancer Cells and Cancer Stem Cells Promotes Metabolic and Tumorigenic Reprogramming Reinforced by Obesity
[Oncogenesis] Elevated ATGL levels in human colon cancer cells relative to non-transformed were augmented by an obesity mediator, oleic acid.
Cancer Stem Cell News
Chemotoxicity-Induced Exosomal lncFERO Regulates Ferroptosis and Stemness in Gastric Cancer Stem Cells
[Cell Death & Disease] Sphere-formation assay was used to estimate the stemness of gastric cancer stem cells. Exosomal lnc-ENDOG-1:1 (lncFERO) was isolated by ultracentrifugation.
Cancer Stem Cell News
Aptamer-Mediated Doxorubicin Delivery Reduces HCC Burden in 3D Organoids Model
[Journal of Controlled Release] Investigators developed a specific aptamer against EpCAM and tested its potential as a drug delivery agent for hepatocellular carcinoma.
Cancer Stem Cell News
pERK-Mediated IL8 Secretion Can Enhance the Migration, Invasion, and Cisplatin Resistance of CD10-Positive Oral Cancer Cells
[BMC Cancer] Researchers hypothesized that IL8 might regulate migration, invasion, and cisplatin resistance of CD10-positive oral cancer cells through the ERK pathway.