cancer stem cells

[Oncogene] Researchers showed that the activation of the RON receptor tyrosine kinase signaling pathway specifically in macrophages supports breast cancer growth and metastasis.

[Cancer Letters] The authors address the noncanonical roles of p53 and their implications in sarcoma initiation and progression.

[Experimental Cell Research] Scientists investigated the expression profile and biological function of lncRNAs in urothelial cancer stem-like cells by microarray analysis.

[Translational Oncology] Researchers found that sensitivity toTemozolomide (TMZ) was suppressed by significantly increasing the major vault protein (MVP) expression in glioblastoma multiforme cells with TMZ resistance.

[Cancer Medicine] After integrating the tumor stemness index based on mRNA expression, immune score, mRNA expression, and clinical information from the TCGA database, scientists screened 380 tumor stemness and immune (TSI)-related genes and constructed a five TSI-specific-gene signature.

[Journal of Controlled Release] Investigators engineered a photodynamic nanoplatform to manipulate breast cancer stem cells against tumor progression and metastasis by not only remolding the disequilibrium state but also blocking the epithelial-mesenchymal transition process.