Tumor Stemness and Immune Infiltration Synergistically Predict Response of Radiotherapy or Immunotherapy and Relapse in Lung Adenocarcinoma

After integrating the tumor stemness index based on mRNA expression, immune score, mRNA expression, and clinical information from the TCGA database, scientists screened 380 tumor stemness and immune (TSI)-related genes and constructed a five TSI-specific-gene signature.