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cardiomyocytes

LncRNA XR_596701 Protects H9c2 Cells against Intermittent Hypoxia-Induced Injury through Regulation of the miR-344b-5p/FAIM3 Axis

[Cell Death Discovery] Gene expressions of XR_596701 and miR-344b-5p were detected by quantitative real-time polymerase chain reaction in intermittent hypoxia-induced H9c2 cells.

Cardiomyocyte IL-1R2 Protects Heart from Ischemia/Reperfusion Injury by Attenuating IL-17RA-Mediated Cardiomyocyte Apoptosis

[Cell Death & Disease] After myocardial ischemia reperfusion surgery, IL-1R2 expression was significantly increased in heart of wild-type mice.

Mechanism of miR-378a-3p Enriched in M2 Macrophage-Derived Extracellular Vesicles in Cardiomyocyte Pyroptosis after MI

[Hypertension Research] An in vitro cell model was established, followed by a comprehensive evaluation of cell viability and pyroptosis. The binding relationships of miR-378a-3p and ELAVL1, HuR, and NLR family pyrin domain containing 3 were analyzed.

Intrinsic Cardiac Adrenergic Cells Contribute to LPS-Induced Myocardial Dysfunction

[Communications Biology] Researchers showed that norepinephrine secretion from intrinsic cardiac adrenergic cells was increased through activation of Toll-like receptor 4 to aggravate myocardial TNF-α production and dysfunction by lipopolysaccharide (LPS).

LncRNA ROR Modulates Myocardial Ischemia-Reperfusion Injury Mediated by the miR-185-5p/CDK6 Axis

[Laboratory Investigation] Researchers revealed that hypoxia/reoxygenation (H/R) treated human cardiac myocytes showed a significantly decreased miR-185-5p expression and increased expression of CDK6 and ROR.

Lycium barbarum Polysaccharide Antagonizes Cardiomyocyte Apoptosis by Inhibiting the Upregulation of GRK2 Induced by I/R Injury, and Salvage Mitochondrial Fission/Fusion Imbalance and AKT/eNOS Signaling

[Cellular Signalling] Scientists found that Lycium barbarum polysaccharide limited myocardial infarct size, improved adverse remodeling, and reduced cell death and oxidative stress.

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