Tag results:
cardiomyocytes
Muscle Cell News
Single-Cell Sequencing Reveals Lineage-Specific Dynamic Genetic Regulation of Gene Expression during Human Cardiomyocyte Differentiation
[PLoS Genetics] During a dynamic process such as cellular differentiation, the overall cell type composition of a tissue (or an in vitro culture) and the gene regulatory profile of each cell can both experience significant changes over time.
Muscle Cell News
Overexpression of the SARS-CoV-2 Receptor Angiotensin Converting Enzyme 2 in Cardiomyocytes of Failing Hearts
[Scientific Reports] Scientists examined the expression of ACE2 in normal hearts and hearts from patients with terminal heart failure.
Muscle Cell News
A20 (TNFAIP3) Alleviates Viral Myocarditis through ADAR1/miR-1a-3p-Dependent Regulation
[BMC Cardiovascular Disorders] A20 was underexpressed and miR-1a-3p was overexpressed in the myocardium of VMC mice as well as in Coxsackie virus B3-infected cardiomyocytes.
Muscle Cell News
Roles and Potential Clinical Implications of Tissue Transglutaminase in Cardiovascular Diseases
[Pharmacological Research] Scientists summarize recent advances in tissue transglutaminase and discuss its role and mechanisms in the progression of various cardiovascular disease and its potential as a diagnostic and therapeutic target.
ESC & iPSC News
Base Editing of Human Pluripotent Stem Cells for Modeling Long QT Syndrome
[Stem Cell Reviews and Reports] Researchers described an optimized stepwise protocol to introduce disease-specific mutations of long QT syndrome into human PSCs.
Muscle Cell News
Skeletal Muscle Derived Musclin Protects the Heart during Pathological Overload
[Nature Communications] Scientists investigated whether the dysregulation of myokine expression from wasting skeletal muscle exaggerated heart failure.