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cardiomyocytes

Vascular Endothelial Growth Factor Ameliorated Palmitate-Induced Cardiomyocyte Injury via JNK Pathway

[Animal] To investigate the preservative effects of vascular endothelial growth factor sensitization on ceramide-mediated programmed cell death of cardiomyocytes, palmitate-induced injury in H9c2 cells was established as an in vitro model.

Stress-Assisted Gold Micro-Wrinkles on a Polymer Cantilever for Cardiac Tissue Engineering

[Colloids and Surfaces B-Biointerfaces] The authors fabricated a unique cantilever-based device, whose surface was structured with stress-assisted micro-wrinkles.

Idarubicin-Induced Oxidative Stress and Apoptosis in Cardiomyocytes: An In Vitro Molecular Approach

[Human & Experimental Toxicology] Scientists investigated the effects of Idarubicin (IDA) on the HL-1 cardiac muscle cell. Different concentrations of IDA were used at different time periods, and the Cell Counting Kit-8; 2,7-dichlorodihydrofluorescein diacetate probe method; and ELISA were used to detect the oxidative stress level.

Fibroblast Transition to an Endothelial “Trans” State Improves Cell Reprogramming Efficiency

[Scientific Reports] Scientists explored a novel strategy leveraging endothelial cell plasticity to enhance reprogramming efficiency. Rat cardiac endothelial cells and fibroblasts were treated with Gata4, Mef2c, and Tbx5 to assess the cardio-differentiation potential of these cells.

Fibroblast-Mediated Intercellular Crosstalk in the Healthy and Diseased Heart

[Febs Letters] The authors review the current knowledge of fibroblast interactions in the healthy, diseased and aging heart.

Modulation of Cell Signaling and Sulfation in Cardiovascular Development and Disease

[Scientific Reports] Immunocytochemical analysis confirmed SULF1/SULF2 expression in endothelial cell lining of blood vessels and in developing cardiomyocytes, but not in the adult cardiomyocytes despite persisting at reduced levels in the adult endothelial cells.

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