cardiomyocytes

[Basic Research in Cardiology] Researchers established an in vitro iPSC model of anthracycline-induced cardiotoxicity (ACT) from patients with an aggressive form of B-cell lymphoma and examined whether doxorubicin-treated ACT-iPSC cardiomyocytes could recapitulate the clinical features exhibited by patients.

[Molecular Biotechnology] Researchers probe the role of Sox9 in cardiomyocyte apoptosis after acute myocardial infarction (AMI). AMI cell model was established in AC16 cells by hypoxia treatment.

[Biomed Research International] Researchers studied the protective effects of nicotinic acid riboside on Dox-induced cardiotoxicity in vivo and in vitro.

[Disease Markers] Ferroptosis may be involved in the occurrence and development of Ischemic heart disease (IHD). Primary cardiomyocytes were treated with H2O2 to simulate the IHD in vitro model.

[Stem Cell Reviews and Reports] Researchers reported human urine cells could be converted into CM-like cells from different donors and the related chromatin accessibility dynamics by assay for transposase accessible chromatin-seq.

[Genomics] Scientists explored the mechanism of human umbilical cord mesenchymal stem cells-derived extracellular vesicles loaded with miR-223 on myocardial infarction. Inflammation, cell biological functions, and fibrosis in vitro were measured.