caspase-9

[Scientific Reports] Scientists attempted to find the role of TLR4 in cardiac fibrosis and apoptosis, and molecular mechanism thereof.

[International Journal of Biological Macromolecules] The well-organized, simplistic, and biological route of AgNPs (AgNPs) was synthesized using shrimp shell extracted chitin as reducing, capping and stabilizing factor under the optimized conditions. The anticancer potential of synthesized biogenic AgNPs was evaluated against human hepatocarcinoma cells.

[Scientific Reports] Cell division cycle 6 (Cdc6)-depleted pancreatic cancer cells significantly inhibited cell proliferation and colony formation, delayed G2/M cell cycle progression, and increased expression of p-histone H3 and cyclin A2 levels.

[International Journal of Biological Macromolecules] Scientists evaluated the inhibitory effects of artesunate on HSP70 and Bcl-2 expression in two breast cancer cell lines, 4T1 and MCF-7.

[Carcinogenesis] A genomewide expression analysis in cell lines led scientists to uncover that activation of ferroptosis and suppression of β-catenin/Wnt-signaling pathways were the key mediators for the anti-cancer and chemosensitizing effects of andrographis.

[Cancer Cell International] Small nucleolar RNA host gene 6 (SNHG6) expression was increased and miR-186 expression was reduced in drug-resistant prostate cancer tissues and cells.