cell proliferation

[International Journal of Stem Cells] Researchers reported the effects of diesel exhaust particles exposure on the properties of human Wharton’s jelly-derived mesenchymal stem cells, including stemness, regeneration, and immunomodulation.

[Cell Biology International] HPV16 E6 silence or overexpression were carried out to evaluate the possible mechanisms of HPV16 E6 function in cervical cancer cells with different HPV16 E6 expression background.

[Proceedings of the National Academy of Sciences of the United States of America] The authors engineered the highly migratory and brain tumor tropic human neural stem cells LM008 to continuously secrete high amounts of functional, stable, full-length antibodies against human epidermal growth factor receptor 2 (HER2) without compromising the stemness of LM008 cells.

[Stem Cells International] Scientists discovered that p57Kip2 (p57), a cyclin-dependent kinase inhibitor canonically inhibiting cell proliferation, played a role in suppressing the pluripotency state of mouse ESCs.

[Oncogene] FGD3, which is involved in regulating the actin cytoskeleton and cell shape, has been reported to inhibit cancer cell migration and predict a favorable prognosis in multiple types of cancer. Researchers conducted a systematic investigation of the cancer-related role of FGD3 in pancreatic cancer.

[DNA and Cell Biology] Scientists analyzed the effects of Ginkgo biloba extract (GBE) administration on TET2 expression in human colorectal cancer (CRC). To investigate the expression profiles of TET2, GBE was used to treat CRC cells.