cell transplantation

[ACS Biomaterials Science & Engineering] Scientists covalently modified alginate with RGD and QK peptides that were injected subcutaneously into immunocompetent mice.

[Pediatric Blood & Cancer] While the majority of patients with complete responses to the brentuximab vedotin with gemcitabine regimen ultimately underwent high-dose chemotherapy and autologous stem cell transplantation (ASCT) consolidation, four subjects, reported herein, achieved durable complete remissions lasting more than four years after the study treatment but without ASCT consolidation.

[Frontiers in Immunology] The authors summarize current evidence from in vitro studies, animal models, and their clinical experience, to support stromal cell therapy in multiple clinical indications.

[Blood] The authors reported the first German real-world data on standard-of-care CAR-T cell therapies with the aim to explore risk factors associated with outcome.

[Scientific Reports] Investigators prepared mitochondria-activated stem cells (MITO cells) for use in transplantation. MITO cells, which were cardiac progenitor cells activated by the mitochondrial delivery of resveratrol with an anti-oxidant and mitochondrial activation effects, were successfully prepared using a mitochondrial targeting nanocarrier.

[Haematologica] The study comprises children with persistent cytopenias, myelodysplastic syndrome, aplastic anemia, or suspected inherited bone marrow failure syndromes, who were referred for genetic evaluation from all pediatric hematology centers in Israel during 2016-2019.